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Dehydroepiandrosterone sulfate
CAS No. 651-48-9
Dehydroepiandrosterone sulfate( Prasterone sulfate | PB-005 | PB005 | PB 005 | DHEA sulfate | DHEAS | )
Catalog No. M27837 CAS No. 651-48-9
Prasterone sulfate is a HSD11B1 expression inhibitor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 80 | In Stock |
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| 10MG | 132 | In Stock |
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| 25MG | 267 | In Stock |
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| 50MG | 425 | In Stock |
|
| 100MG | 621 | In Stock |
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| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameDehydroepiandrosterone sulfate
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NoteResearch use only, not for human use.
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Brief DescriptionPrasterone sulfate is a HSD11B1 expression inhibitor.
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DescriptionPrasterone sulfate is a HSD11B1 expression inhibitor.(In Vitro):Dehydroepiandrosterone sulfate selectively increases the length of neurites containing the dendritic marker MAP-2 and increases neuronal excitability when directly applied to septal-preoptic neurons.(In Vivo):Chronic administration of Dehydroepiandrosterone sulfate produces a dose-dependent effect on performance. In male Sprague-Dawley rats, Dehydroepiandrosterone sulfate (5-20 mg/kg; s.c.) is significantly effective in improving latency to reach the platform.
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In Vitro——
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In VivoAnimal Model:Sixty-four male Sprague-Dawley rats, approximately 90 days of age (300-400 g).Dosage:5, 10, or 20 mg/kg.Administration:Subcutaneous injection starting 7 days post-surgery and 1 h prior to all behavioral testing.Result:Significantly effective in improving latency to reach the platform as compared to injured rats receiving vehicle.
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SynonymsPrasterone sulfate | PB-005 | PB005 | PB 005 | DHEA sulfate | DHEAS |
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PathwayOthers
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TargetOther Targets
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RecptorFLT3
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Research Area——
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Indication——
Chemical Information
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CAS Number651-48-9
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Formula Weight368.49
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Molecular FormulaC19H28O5S
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (271.38 mM)
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SMILES[H][C@@]12CCC(=O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC=C2C[C@H](CC[C@]12C)OS(O)(=O)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.A Eriksson, et al. The Novel Tyrosine Kinase Inhibitor AKN-028 Has Significant Antileukemic Activity in Cell Lines and Primary Cultures of Acute Myeloid Leukemia. Blood Cancer J. 2012 Aug 3;2(8):e81.
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